Description of Work
AETIONOMY has 10 academic partners (of which 4 are clinical partners), 2 SMEs and 4 EFPIA partners. The 4 committed partners (UCB; Novartis, SARD & BI), have allocated resources as well as a substantial financial support of in-kind contribution over the entire project. The AETIONOMY project is organised in 5 work packages. Work packages 1, 2, 4 and 5 have been pre-defined in the call text, so that only for WP3 were we free to chose a topic and title which is now called “clinical study”, as this reflects the nature of the clinical validation efforts.
AETIONOMY will run for 5 years as of 1 January 2014 (60 months). The majority of activities dealing with the knowledge base, the disease modelling, the organisation of the data cube, the capturing and representation of expert knowledge, the identification of omics-indices and clinical indices and the main data mining part will all take place within the first 36 months of the project. From the first year on, we will involve the clinical partners in AETIONOMY; initially focusing on gathering their expert knowledge, but from year two onwards they will be recruiting patients. The first testing of identified testable mechanisms will start in year 3 of AETIONOMY.