AETIONOMY Knowledge base

AETIONOMY’s Knowledge base (AKB)' is the unification point of the knowledge and data management on Neurodegeneration with a main focus on Alzheimer’s and Parkinson’s diseases. It includes

• comprehensive overviews on specific public, clinical and OMICS indices relevant to Neurodegeneration;
• values for such indices at retrospective and prospective studies available at different sites; and
• available OMICS Data.

Analytical results can be calculated by the underlying tranSMART system features. As a result of these activities all components for data storage, analytical results management and incorporated data are integrated into this knowledge platform for Neurodegeneration. Please check the 'AETIONOMY prospective study' – Organising mechanistic knowledge about neurodegenerative diseases for the improvement of drug development and therapy – to get access to this unification point.

NeuroMMSig is a knowledge base representing essential pathophysiology mechanisms of neurodegenerative diseases. Together with dedicated algorithms, this knowledge base forms the basis for a “mechanism-enrichment server” that supports the mechanistic interpretation of multiscale, multimodal clinical data.